Modalert is a brand-name version of the generic medication Modafinil. Sun Pharmaceuticals manufactures 100 mg and 200 mg tablets, the majority of which are manufactured in India and sold through internet pharmacies.
Due to the exorbitant price of Provigil, the most popular generic brand of Modafinil, Modalert has gained popularity among all users of this wakefulness-promoting medication.
Modalert is frequently included in the prominent category of Nootropics. It is also referred to as a cognitive enhancer or drug chip because it is intended to increase memory, learning, and other cognitive processes.
Initially, Modalert 200 mg was designed to promote alertness, wakefulness, and vigilance in those with sleep disorders such as narcolepsy sleep apnea and others. It is also known to improve mental performance, attentiveness, and concentration.
Even a proposal to legalize Modafinil for the treatment of ADHD existed. It was eventually concluded by the FDA that the drug was suitable for the treatment of ADHD symptoms in youngsters, a judgment that is now seen as very contentious. Sun Pharma Modalert is believed to have a lesser risk of adverse side effects, addiction, and withdrawal than other ADHD medications, such as Ritalin and Adderall.
History of Modafinil
Before you buy Modafinil, you should perhaps know its History! Modafinil was developed as a derivative of Adrafinil in France during the late 1970s. In 1974, adrafinil and several additional sulfinyl benzhydryl compounds were found. Extensive study on Adrafinil led to its ultimate use as a treatment for narcolepsy sleep disorders, beginning in 1986 in France.
Modafinil was discovered during the experiment to investigate the mechanism of action of Adrafinil. Adrafinil was discovered to be metabolized in the body into the active chemical Modafinil and the inert substance modafinil acid.
After additional research and development, scientists were able to directly synthesize Modafinil. Although Modafinil and its parent chemical, Adrafinil, have essentially comparable effects, Modafinil is today considerably more popular than Adrafinil because it is significantly more potent and faster.
Modafinil, like the pre-drug Adrafinil, was initially studied in humans for narcolepsy. Narcolepsy is a sleep-wake disorder characterized by extreme daytime sleepiness, potentially poor nocturnal sleep, trouble remaining awake during the day, and sporadic daily naps.
In many double-blind, placebo-controlled studies, Modafinil was proven to be much more effective than placebo at enhancing wakefulness and reducing daytime sleepiness in narcolepsy patients. In 1998, the FDA authorized modafinil as a therapy for narcolepsy in the United States.
In a similar vein, Modafinil has been the subject of extensive research for other sleep disorders characterized by excessive drowsiness, including shift work sleep disorder and obstructive apnea/hypopnea syndrome.
Modalert, Sleep & Wakefulness
Shift Work sleep disorder is a disorder that can develop when regular circadian rhythms (daily/wake cycles matching to day and night) are disturbed by night and late shifts. People with this illness frequently feel excessive tiredness when awake (typically late at night and at night), as well as sleeplessness when attempting to sleep (usually during the day).
Due to the fact that Modafinil is a known wakefulness-promoting medicine (a eugeroic agent), research has been conducted to improve wakefulness in individuals with Major sleep disorders. Compared to a placebo, Modafinil administered one hour before a work shift enhanced Psychomotor Vigilance Test performance, as measured by fewer attention lapses.
The Obstructive Apnea/Hypopnea Syndrome (OSAH) is a disorder that involves sleep-related breathing impairment or stoppage. Involuntary relaxation of the muscles that maintain the tongue and soft palate in place can restrict the airway. Hypopnoea refers to a partial restriction of the airway and shallow breathing, whereas sleep apnoea refers to the cessation of breathing caused by a total obstruction of the airway.
People with OSA frequently suffer significant daytime sleepiness due to the poor quality of sleep produced by numerous episodes of breathing during the night. Modafinil has been licensed as an adjunct treatment for obstructive sleep apnea (OSA) to relieve this symptom of the disorder, when used in conjunction with treatment for the disease itself, which is typically a continuous positive airway pressure (CPAP) equipment worn while sleeping.
Benefits of Modalert
Several of Modalert’s mechanisms of action are still not fully understood. It appears incapable of penetrating the blood-brain barrier and entering the central nervous system.
It has been found to considerably limit the reuptake of this neurotransmitter in the brain by acting on the Dopamine transporter. This results in an increase in the level of dopamine, which can enhance circulatory motivation, mental attention and endurance, and mood.
Modalert is primarily recognized for affecting brain histamine levels. This monoamine hormone is an essential component of the system that regulates the sleep-wake cycle and affects daytime alertness.
Sleep is believed to be a hormone-induced state; by stimulating the natural levels of these hormones, Modalert can boost daytime alertness and prevent weariness caused by prolonged stress.
This medicine has also been reported to affect the brain’s norepinephrine, serotonin, and orexin systems. In addition to being a significant antioxidant that can improve nerve cell health, other studies have indicated that it has a powerful neuroprotective impact.
Buy Modafinil Online
Modafinil, particularly the branded versions such as Provigil, is a very expensive medication, costing hundreds of thousands of dollars every month. Due to the high demand for this medication, numerous online pharmacies offer it at a significantly lower price.
Despite the fact that some respectable and authorized pharmacies require a prescription to buy Modafinil, many others do not. Frequently, the safety and validity of the Modafinil tablets sold by these pharmacies are doubtful. It is crucial to investigate the source of your purchases to prevent purchasing counterfeit goods.
Many people use Adrafinil, which is not a regulated substance and does not require a prescription, for this reason. There are some nations that will allow you to buy Modafinil or buy Modalert online and then import these tablets lawfully, but you should verify with the local authorities to confirm this.
Interesting Related Article: “What is sleep apnea: symptoms and treatment“