4-Step Skincare Routine: The Science Behind Sisel’s Natrience™ Ingredients

Applying one of Sisel’s Natrience™ skin care product on hand as part of a four-step skin care routine for healthy, radiant skin. Discover the benefits of Sisel Natrience™ ingredients in protecting, hydrating, and rejuvenating skin with scientifically backed formulations.

Healthy, radiant skin requires more than just an occasional scrub or moisturizer—it demands a science-backed, consistent skin care routine. At Sisel International, the focus is on delivering superior skin care through a combination of nature and advanced technology. The Natrience™ skin care line is a testament to this philosophy, providing products that work synergistically to protect, hydrate, and rejuvenate your skin. 

In this article, we’ll break down Sisel’s Natrience™ four-step skin care routine and explore how each step is scientifically designed to contribute to better skin health. From cleansing to protecting, every part of the routine is crucial in maintaining your skin’s natural balance and helping it look its best.

Tom Mower Jr. and Tom Mower Sr.: Leading Sisel International’s Vision of Innovation and Excellence

At the heart of Sisel International’s commitment to delivering exceptional personal care and skin care products is the vision of its founders, Tom Mower Sr. (also known as Thomas Mower Sr.) and Tom Mower Jr. (also known as Thomas Mower Jr.). Since its inception, Sisel International has focused on formulating safe and effective products, guided by the Mower family’s core philosophy of eliminating harmful ingredients from everyday products. 

This dedication is embodied in the Sisel Safe® standard, which ensures that all products are free from potentially toxic chemicals such as parabens, sulfates, and synthetic fragrances.

Tom Mower Sr. pioneered this mission with a commitment to raising awareness about the dangers of common toxins in personal care products. His vision was to innovate with safer alternatives and set new industry standards for health and safety. His son, Tom Mower Jr., has continued this legacy, expanding Sisel’s product line with cutting-edge research and innovative formulations. 

Under the leadership of both Tom Mower Sr. and Tom Mower Jr., Sisel International has evolved into a global leader known for its rigorous testing, high-quality ingredients, and unwavering commitment to consumer wellness.

The Mower family’s vision for Sisel International extends beyond product development. It’s about creating a community that values transparency, integrity, and proactive health choices. By choosing Sisel’s Natrience™ skin care line and other Sisel Safe® products, you are not just enhancing your skin care routine—you are supporting a company that prioritizes long-term health and environmental responsibility. 

Whether through the advanced formulations in the Natrience™ skin care line or the innovative personal care products, Sisel International continues to push the boundaries of what’s possible in toxin-free, effective personal care.

This commitment to quality and safety means that every product you use from Sisel is backed by decades of research and dedication to improving lives. As Thomas Mower Jr. leads with passion and innovation, continuing the vision set by Thomas Mower Sr., Sisel International is poised to redefine the standards of personal care and wellness, setting new benchmarks for excellence in the industry.

The Science of Skin Care: Breaking Down a 4-Step Routine

A well-rounded skin care routine is essential for maintaining healthy, radiant skin. Sisel’s Natrience™ scientifically formulated four-step regimen ensures your skin receives the care it needs at every stage. By following the steps of Cleanse, Treat, Moisturize, and Protect, you provide your skin with everything it needs to stay balanced, hydrated, and protected. Let’s explore how each step contributes to overall skin health.

Step 1: Cleanse

Cleansing is the first and most critical step in any skin care routine. It helps remove dirt, oil, makeup, and impurities that accumulate throughout the day. Without proper cleansing, these elements can clog pores, lead to breakouts, and prevent the absorption of skin care treatments. 

Sisel Natrience™ Pure Balance Jelly Cleanser is a gentle yet effective hydrating cleanser that not only purifies but also lightly exfoliates the skin, removing dead cells and promoting cell turnover. This cleanser contains Sodium Hyaluronate, which helps maintain skin hydration while cleansing away excess oils, leaving your skin refreshed and prepped for the next steps​.

Step 2: Treat

Once the skin is clean, it’s ready for targeted treatments to address specific concerns, such as fine lines, wrinkles, or uneven skin tone.Sisel Natrience Cell Anew Perfecting Serum is packed with powerful ingredients like Hydroxypinacolone Retinoate, a gentle retinol alternative that promotes cell turnover and reduces the appearance of fine lines without causing irritation. 

This treatment deeply hydrates the skin while defending against environmental stressors like blue light and pollution. Using a serum in this step ensures that active ingredients penetrate deeply into the skin, providing maximum benefits and setting the stage for moisturization.

Step 3: Moisturize

Moisturizing is essential for locking in hydration and reinforcing the skin’s natural barrier. Sisel Natrience™ Hydra Light Repair Lotion delivers lightweight yet effective hydration, replenishing the skin’s moisture levels and protecting against environmental damage. Ingredients like Ceramides and Beta Glucan support the skin’s barrier function, preventing moisture loss and enhancing the skin’s resilience to external aggressors. Moisturizing helps to soften the skin, smooth out texture, and prepare it for the final step of protection.

Step 4: Protect

Protection is key to maintaining healthy, youthful skin over time. The final step in the routine is protection from environmental damage, particularly UV rays and blue light. Sisel Natrience™ Skin Shield Mineral Sunscreen SPF 30 offers broad-spectrum protection against both UVA and UVB rays, while also shielding the skin from the harmful effects of blue light emitted by digital devices​. This step is crucial for preventing premature aging, sunspots, and wrinkles, ensuring that your skin stays protected and radiant throughout the day.

By following these four essential steps, your skin will not only look healthier but will also be better equipped to absorb the beneficial ingredients in each product. Cleanse, Treat, Moisturize, and Protect—this simple yet effective routine ensures long-term skin health and vitality.

Why Sisel’s Natrience™ Ingredients Outperform Competitors

In the competitive skin care market, not all ingredients are created equal. Sisel’s Natrience™ skin care line sets itself apart by using scientifically proven, high-performing ingredients that deliver real results. When comparing Sisel Natrience™ to well-known brands like La Roche-Posay and Olay, the quality and efficacy of the ingredients stand out. While many competitors rely on generic formulations, Sisel Natrience™ utilizes powerful active ingredients that target hydration, aging, and environmental protection, providing long-lasting benefits for the skin.

One of the hero ingredients in the Natrience™ line is Sodium Hyaluronate, a superior form of Hyaluronic Acid. Known for its ability to deeply penetrate the skin, it provides immediate and long-lasting hydration, reducing moisture loss and promoting a smoother, plumper appearance​. This level of hydration is crucial for maintaining skin elasticity and reducing the appearance of fine lines, a key concern for many skin care users.

Another standout ingredient is Hydroxypinacolone Retinoate, a gentler yet highly effective alternative to traditional retinol. Unlike retinol, which can often cause irritation and redness, Hydroxypinacolone Retinoate delivers the same anti-aging benefits without the harsh side effects. It accelerates cell turnover, smooths fine lines and wrinkles, and evens out skin tone, making it one of the most effective retinoids available.

Spirulina Maxima, an antioxidant-rich algae, offers protection against environmental damage, including UV rays and blue light exposure from digital devices. This ingredient helps to protect against environmental stressors. While competitor brands may include basic sunscreens, Natrience™ focus on combining antioxidant protection with hydration ensures that the skin is not only shielded from damage but also nourished.

By incorporating these potent, natural ingredients, Sisel Natrience™ outperforms competitors in the critical areas of hydration, anti-aging, and environmental protection. The combination of these ingredients provides a comprehensive approach to skin care, offering more than just surface-level improvements. The Natrience™ line supports long-term skin health while delivering visible results with products like Cell Anew Perfecting Serum and Pure Balance Jelly Cleanser.

Deepening the Science: Understanding the Key Ingredients in Sisel Natrience™ Products

Sodium Hyaluronate

Sodium Hyaluronate (SH) is a salt form of Hyaluronic Acid (HA) with a lower molecular weight, allowing it to penetrate deeper into the skin compared to regular HA. Its smaller molecular structure makes it highly effective at delivering hydration deep within the skin, improving moisture retention in the dermis.

  • Molecular Action: Sodium Hyaluronate binds to water molecules, holding up to 1,000 times its weight in water. This boosts skin hydration, increases elasticity, and plumps the skin, reducing the appearance of fine lines and wrinkles.
  • Specific Benefits: While standard Hyaluronic Acid sits more superficially on the skin, Sodium Hyaluronate penetrates deeply, ensuring long-lasting hydration. This ingredient is particularly effective for skin that struggles with moisture retention or feels tight and dry.
  • Relevant Study: A study titled “Effect of Sodium Hyaluronate on Antioxidant and Anti-Ageing Activities in Caenorhabditis elegans,” concluded that “SH provides potential applications in anti-ageing and anti-oxidation and regulates physiological function.”

Hydroxypinacolone Retinoate (HPR)

Hydroxypinacolone Retinoate is a next-generation retinoid that provides the benefits of retinol without the usual irritation associated with it. Retinoids are well-known for their anti-aging properties, but traditional retinoids, like retinol, can cause redness and peeling.

  • Molecular Action: HPR works by directly binding to retinoid receptors in the skin cells, promoting cell turnover and collagen production. Unlike retinol, HPR does not need to undergo a multi-step conversion process, which makes it more potent while being gentler on the skin.
  • Specific Benefits: HPR offers retinol-like benefits—reduction of fine lines, smoothing of skin texture, and evening out of skin tone—without the irritation often caused by retinol. This makes it ideal for those with sensitive skin or first-time retinoid users.
  • Relevant Study: A study, titled “Antiaging effects of retinoid hydroxypinacolone retinoate on skin models,” published in JAAD, concluded that “HPR is an effective alternative to ATRA [All-trans retinoic acid] and other less potent retinoids in the treatment of aging skin without the detrimental side-effects.”

Spirulina Maxima (Algae Extract)

Spirulina Maxima is a blue-green algae rich in antioxidants, vitamins, and minerals, which protect the skin from environmental damage like UV exposure and blue light.

  • Molecular Action: This algae’s antioxidant properties neutralize free radicals, which are unstable molecules caused by UV rays and pollution that break down collagen and lead to premature aging.
  • Specific Benefits: Spirulina Maxima helps protect the skin from oxidative stress and inflammation, leading to fewer wrinkles, less hyperpigmentation, and an overall healthier skin barrier. It’s also rich in amino acids, which promote skin regeneration and repair.
  • Relevant Study: A study published in Cosmetics found that as an antioxidant, Spirulina may reduce skin hyperpigmentation and protect skin against sun-induced damages

Understanding Sisel Safe®: Ingredient Transparency for Healthier Skin

In an industry saturated with products that often contain hidden toxins, Sisel International stands out with its Sisel Safe® standard—a commitment to transparency and safety. The Sisel Safe® promise guarantees that all products in the Natrience™ skin care line are free from harmful chemicals like parabens, sulfates, and synthetic fragrances commonly found in many competitor brands​. This transparency allows consumers to trust that they are using products that support their skin health without compromising safety.

The Sisel Safe® standard is not just about what is left out of the products but also about what is included. Each ingredient is carefully selected for its proven efficacy and safety, ensuring that the formulas provide maximum benefits for the skin. For example, Sodium Hyaluronate delivers deep hydration, while Hydroxypinacolone Retinoate gently encourages cell turnover, minimizing the appearance of fine lines without irritation.

Competitor brands, like La Roche-Posay and Olay, may offer similar active ingredients, but they often combine them with less skin-friendly chemicals that can cause irritation, disrupt the skin’s barrier, or contribute to long-term damage. In contrast, Sisel Natrience™ products are formulated with natural, bioavailable ingredients that work in harmony with your skin, supporting its natural functions and promoting resilience.

The benefits of using Sisel Safe® products extend beyond short-term results. Users can enjoy healthier, more resilient skin over the long term by eliminating exposure to toxins. Whether it’s Pure Balance Jelly Cleanser gently removing impurities​ or Skin Shield Mineral Sunscreen SPF 30 protecting against UVA, UVB, and blue light damage​, Sisel Safe® ensures that every product nourishes and protects your skin at every step of your routine.

Take the Next Step Towards Radiant, Healthy Skin

Incorporating Sisel Natrience™ 4-step skin care routine—Cleanse, Treat, Moisturize, and Protect—into your daily regimen is the key to achieving healthy, radiant skin. Each product is designed with scientifically backed ingredients that work in harmony to hydrate, protect, and rejuvenate your skin, ensuring long-term results. Whether you’re addressing fine lines, boosting hydration, or safeguarding your skin from environmental damage, Sisel Natrience™ provides everything your skin needs to thrive.

Ready to experience the power of nature and science combined? Explore the full range of Sisel Natrience™ products today and take the first step towards healthier, glowing skin. Visit Sisel International to discover more and transform your skin care routine with products that deliver results you can trust. Your best skin care routine starts here!


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